By Dr. David Harvey, MD, FAAD, FACP
What are Omega 3 fatty acids?

Fig. 1 Salvia Hispanica
Omega-3 fatty acids are considered essential fatty acids. They are essential to human health but cannot be manufactured by the body. For this reason, omega-3 fatty acids must be obtained from food. Omega-3 fatty acids can be found in fish, such as salmon, tuna, and halibut, certain plants (including purslane), nut oils, and the natural peruvian grain Salvia Hispanica (Fig. 1). Omega-3 fatty acids play a crucial role in brain function as well as normal growth and development.
The American Heart Association recommends eating fish or fish oils (Fig. 2) (particularly fatty fish such as mackerel, lake trout, herring, sardines, albacore tuna, and salmon) at least 2 times a week. It is advised that pregnant women and mothers, nursing mothers, young children, and women who might become pregnant not eat several types of fish, including swordfish, shark, and king mackerel. They can take omega-3 fatty acids in quality dietary supplements that are certified mercury-free by a reputable third-party lab.

Fig. 2 Fish Oil
There are three major types of omega 3 fatty acids that are ingested in foods and used by the body:
Alpha-linolenic acid (ALA)
Eicosapentaenoic acid (EPA)
Docosahexaenoic acid (DHA).
Once eaten, the body converts ALA to EPA and DHA, the two types of omega-3 fatty acids more readily used by the body. Extensive research indicates that omega-3 fatty acids reduce inflammation and help prevent risk factors associated with chronic diseases such as heart disease, cancer (skin cancer, prostate cancer, colon cancer), and arthritis. They are also helpful for blood pressure control, arthrosclerosis and diabetes mellitus. These essential fatty acids are highly concentrated in the brain and appear to be particularly important for cognitive (brain memory and performance) and behavioral function. In fact, infants who do not get enough omega-3 fatty acids from their mothers during pregnancy are at risk for developing vision and nerve problems as well as atopic dermatitis. Symptoms of omega-3 fatty acid deficiency include extreme tiredness (fatigue), poor memory, dry skin, heart problems, mood swings or depression, and poor circulation.
It is important to maintain an appropriate balance of omega-3 and omega-6 (another essential fatty acid) in the diet, as these two substances work together to promote health. Omega-3 fatty acids help reduce inflammation, and most omega-6 fatty acids tend to promote inflammation. An inappropriate balance of these essential fatty acids contributes to the development of disease while a proper balance helps maintain and even improve health. A healthy diet should consist of roughly 2 - 4 times more omega-6 fatty acids than omega-3 fatty acids. Many biochemists and physicians feel that the imbalance of omega-6/omega-3 fatty acid ratio is a significant factor in the rising rate of inflammatory disorders in the United States.
Uses in Dermatology

Fig 3. Acne Vulgaris
Clinical studies suggest that omega-3 fatty acids may be helpful in treating a variety of health conditions. In dermatology the benefits include, acne vulgaris(Fig 3) due to help with blood sugar control, anxiety induced(neurodermatitis), photodermatitis, psoriasis, burns, dry skin, systemic lupus vulgaris, and even nonmelanoma skin cancer (Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC)). Specifically, A prospective study found that higher intakes of omega-3 fatty acids were associated with lower BCC risk. However, when non-white males were removed the association weakened (Black and Rhodes 2006 from van Dam et al. 2000). Another population-based study was able to demonstrate a lower risk of SCC with higher intakes of omega-3 fatty acids (Black and Rhodes 2006 from Hakim et al. 2000).
Risks
Omega-3 fatty acids should be used cautiously by people who bruise easily, have a bleeding disorder, or take blood-thinning medications, including warfarin (Coumadin™) or clopidogrel (Plavix™), because excessive amounts of omega-3 fatty acids (> 3 grams a day) may lead to bleeding. Ask your doctor if you are unsure about taking omega 3 fatty acid supplements.
Summary
Omega-3 fatty acids may be just what the dermatologist ordered for your skin health issues. If you are interested to learn more about the benefits of Omega 3 fatty acids, please click here or call 904-285-5880.